Substance and medication use during pregnancy can have severe health issues for expecting mothers and their newborns. NAS or Neonatal abstinence syndrome has tripled in the last 10 years, and newborns who have been diagnosed with NAS are more likely to have trouble breathing, feeding difficulties, seizures, and a low birth weight. When used with other universal screening tools, UDT may help a physician to proactively study medication use, addition, and misuse that may result in harming the developing fetus and the mother. Test results will offer an opportunity for the patient education and assessment regard risk for the mother and child.